Genetic and Epigenetic Changes of Components Affecting the WNT Pathway in Colorectal Carcinomas Stratified by Microsatellite Instability

An unselected series of 310 colorectal carcinomas, stratified according to microsatellite instability (MSI) and DNA ploidy, was examined for mutations and/or promoter hypermethylation of five components of the WNT signaling cascade [APC, CTNNB1 (encoding β-catenin), AXIN2, TCF4, and WISP3] and three...

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Detalhes bibliográficos
Main Authors: Thorstensen, Lin, Lind, Guro E, Løvig, Tone, Diep, Chieu B, Meling, Gunn I, Rognum, Torleiv O, Lothe, Ragnhild A
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501125/
https://ncbi.nlm.nih.gov/pubmed/15802015
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