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PDCD10 (CCM3) REGULATES BRAIN ENDOTHELIAL BARRIER INTEGRITY IN CEREBRAL CAVERNOUS MALFORMATION TYPE 3: ROLE OF CCM3-ERK1/2-CORTACTIN CROSS-TALK

Impairment of brain endothelial barrier integrity is critical for cerebral cavernous malformation (CCM) lesion development. The current study investigates changes in tight junction (TJ) complex organization when PDCD10 (CCM3) is mutated/depleted in human brain endothelial cells. Analysis of lesions...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Acta Neuropathol
मुख्य लेखकों: Stamatovic, Svetlana M., Sladojevic, Nikola, Keep, Richard F., Andjelkovic, Anuska V.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618087/
https://ncbi.nlm.nih.gov/pubmed/26385474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1479-z
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