PDCD10 (CCM3) REGULATES BRAIN ENDOTHELIAL BARRIER INTEGRITY IN CEREBRAL CAVERNOUS MALFORMATION TYPE 3: ROLE OF CCM3-ERK1/2-CORTACTIN CROSS-TALK

Impairment of brain endothelial barrier integrity is critical for cerebral cavernous malformation (CCM) lesion development. The current study investigates changes in tight junction (TJ) complex organization when PDCD10 (CCM3) is mutated/depleted in human brain endothelial cells. Analysis of lesions...

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Detaylı Bibliyografya
Yayımlandı:Acta Neuropathol
Asıl Yazarlar: Stamatovic, Svetlana M., Sladojevic, Nikola, Keep, Richard F., Andjelkovic, Anuska V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618087/
https://ncbi.nlm.nih.gov/pubmed/26385474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1479-z
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