Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regions

Transcription factors canonically bind nucleosome-free DNA, making the positioning of nucleosomes within regulatory regions crucial to the regulation of gene expression. Using the assay of transposase accessible chromatin (ATAC-seq), we observe a highly structured pattern of DNA fragment lengths and...

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Detalles Bibliográficos
Publicado en:Genome Res
Autores principales: Schep, Alicia N., Buenrostro, Jason D., Denny, Sarah K., Schwartz, Katja, Sherlock, Gavin, Greenleaf, William J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Method
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617971/
https://ncbi.nlm.nih.gov/pubmed/26314830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.192294.115
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