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Allosteric Transcriptional Regulation via changes in the Overall Topology of the Core Promoter
Many transcriptional activators act at a distance from core promoter elements and work by recruiting RNA polymerase through protein-protein interactions. We show here how the prokaryotic regulatory protein CueR both represses and activates transcription by differentially modulating local DNA structu...
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| Udgivet i: | Science |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4617686/ https://ncbi.nlm.nih.gov/pubmed/26293965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa9809 |
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