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Chromosomal Instability, Aneuploidy, and Gene Mutations in Human Sporadic Colorectal Adenomas

Whether in vivo specific gene mutations lead to chromosomal instability (CIN) and aneuploidy or viceversa is so far not proven. We hypothesized that aneuploidy among human sporadic colorectal adenomas and KRAS2 and APC mutations were not independent. Additionally, we investigated if 1p34–36 deletion...

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Detalhes bibliográficos
Publicado no:Cell Oncol
Main Authors: Giaretti, Walter, Molinu, Silvia, Ceccarelli, Jenny, Prevosto, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617587/
https://ncbi.nlm.nih.gov/pubmed/15623940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2004/816591
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