Chromosomal Instability, Aneuploidy, and Gene Mutations in Human Sporadic Colorectal Adenomas

Whether in vivo specific gene mutations lead to chromosomal instability (CIN) and aneuploidy or viceversa is so far not proven. We hypothesized that aneuploidy among human sporadic colorectal adenomas and KRAS2 and APC mutations were not independent. Additionally, we investigated if 1p34–36 deletion...

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Bibliographic Details
Published in:Cell Oncol
Main Authors: Giaretti, Walter, Molinu, Silvia, Ceccarelli, Jenny, Prevosto, Claudia
Format: Artigo
Language:Inglês
Published: IOS Press 2004
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617587/
https://ncbi.nlm.nih.gov/pubmed/15623940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2004/816591
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