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Specific K-ras2 Mutations in Human Sporadic Colorectal Adenomas Are Associated with DNA Near-Diploid Aneuploidy and Inhibition of Proliferation

Recent studies indicate that p21ras proteins mediate their multiple cell functions through interactions with multiple effectors and that the number of new effectors is growing. We recently reported that K-ras2 mutations in human colorectal adenomas were associated with chromosome instability and pro...

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Bibliographic Details
Main Authors: Giaretti, Walter, Rapallo, Anna, Geido, Elio, Sciutto, Andrea, Merlo, Franco, Risio, Mauro, Rossini, Francesco P.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 1998
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853049/
https://ncbi.nlm.nih.gov/pubmed/9777951
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