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Engineered bacterial outer membrane vesicles with enhanced functionality

We have engineered bacterial outer membrane vesicles (OMVs) with dramatically enhanced functionality by fusing several heterologous proteins to the vesicle-associated toxin ClyA of Escherichia coli. Similar to native unfused ClyA, chimeric ClyA fusion proteins were found localized in bacterial OMVs...

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Detalles Bibliográficos
Publicado en:J Mol Biol
Autores principales: Kim, Jae-Young, Doody, Anne M., Chen, David J., Cremona, Gina H., Putnam, David, DeLisa, Matthew P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617544/
https://ncbi.nlm.nih.gov/pubmed/18511069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.03.076
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