Foxp3-dependent Transformation of Human Primary CD4+ T Lymphocytes by the Retroviral Protein Tax

The retroviral Tax proteins of human T cell leukemia virus type 1 and 2 (HTLV-1 and -2) are highly homologous viral transactivators. Both viral proteins can immortalize human primary CD4+ memory T cells, but when expressed alone they rarely transform T cells. In the present study, we found that the...

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Bibliographic Details
Published in:Biochem Biophys Res Commun
Main Authors: Chen, Li, Liu, Dan, Zhang, Yang, Zhang, Huan, Cheng, Hua
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617533/
https://ncbi.nlm.nih.gov/pubmed/26381169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.09.063
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