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In vivo impact of a 4 bp deletion mutation in the DLX3 gene on bone development

Distal-less 3 (DLX3) gene mutations are etiologic for Tricho-Dento-Osseous syndrome. To investigate the in vivo impact of mutant DLX3 on bone development, we established transgenic (TG) mice expressing the c.571_574delGGGG DLX-3 gene mutation (MT-DLX3) driven by a mouse 2.3 Col1A1 promoter. Microcom...

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Bibliografiske detaljer
Udgivet i:Dev Biol
Main Authors: Choi, S.J., Roodman, G.D., Feng, J.Q., Song, I.S., Amin, K., Hart, P.S., Wright, J.T., Haruyama, N., Hart, T.C.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617241/
https://ncbi.nlm.nih.gov/pubmed/18996110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.10.014
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