Mutant DLX 3 disrupts odontoblast polarization and dentin formation

Tricho-dento-osseous (TDO) syndrome is an autosomal dominant disorder characterized by abnormalities in the thickness and density of bones and teeth. A 4-bp deletion mutation in the Distal-Less 3 (DLX3) gene is etiologic for most cases of TDO. To investigate the in vivo role of mutant DLX3 (MT-DLX3)...

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Détails bibliographiques
Auteurs principaux: Choi, S.J., Song, I.S., Feng, J.Q., Gao, T., Haruyama, N., Gautam, P., Robey, P.G., Hart, Thomas C.
Format: Artigo
Langue:Inglês
Publié: 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945701/
https://ncbi.nlm.nih.gov/pubmed/20510228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.05.499
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