The BioPlex Network: A Systematic Exploration of the Human Interactome

Protein interactions form a network whose structure drives cellular function and whose organization informs biological inquiry. Using high-throughput affinity-purification mass spectrometry, we identify interacting partners for 2,594 human proteins in HEK293T cells. The resulting network (BioPlex) c...

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Publicado no:Cell
Main Authors: Huttlin, Edward L., Ting, Lily, Bruckner, Raphael J., Gebreab, Fana, Gygi, Melanie P., Szpyt, John, Tam, Stanley, Zarraga, Gabriela, Colby, Greg, Baltier, Kurt, Dong, Rui, Guarani, Virginia, Vaites, Laura Pontano, Ordureau, Alban, Rad, Ramin, Erickson, Brian K., Wühr, Martin, Chick, Joel, Zhai, Bo, Kolippakkam, Deepak, Mintseris, Julian, Obar, Robert A., Harris, Tim, Artavanis-Tsakonas, Spyros, Sowa, Mathew E., DeCamilli, Pietro, Paulo, Joao A., Harper, J. Wade, Gygi, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617211/
https://ncbi.nlm.nih.gov/pubmed/26186194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.06.043
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