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Direct detection of ABCA1-dependent HDL formation based on lipidation-induced hydrophobicity change in apoA-I

ABCA1 mediates the efflux of cholesterol and phospholipids into apoA-I to form HDL, which is important in the prevention of atherosclerosis. To develop a novel method for the evaluation of HDL formation, we prepared an apoA-I-POLARIC by labeling the specific residue of an apoA-I variant with a hydro...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Omura, Risa, Nagao, Kohjiro, Kobayashi, Norihiro, Ueda, Kazumitsu, Saito, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617144/
https://ncbi.nlm.nih.gov/pubmed/25214539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D049445
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