An Xist-activating antisense RNA required for X-chromosome inactivation

The transcriptional imbalance due to the difference in the number of X chromosomes between male and female mammals is remedied through X-chromosome inactivation, the epigenetic transcriptional silencing of one of the two X chromosomes in females. The X-linked Xist long non-coding RNA functions as an...

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Udgivet i:Nat Commun
Main Authors: Sarkar, Mrinal K., Gayen, Srimonta, Kumar, Surinder, Maclary, Emily, Buttigieg, Emily, Hinten, Michael, Kumari, Archana, Harris, Clair, Sado, Takashi, Kalantry, Sundeep
Format: Artigo
Sprog:Inglês
Udgivet: Nature Pub. Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4616153/
https://ncbi.nlm.nih.gov/pubmed/26477563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9564
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