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Structural analyses of the CRISPR protein Csc2 reveal the RNA-binding interface of the type I-D Cas7 family

Upon pathogen invasion, bacteria and archaea activate an RNA-interference-like mechanism termed CRISPR (clustered regularly interspaced short palindromic repeats). A large family of Cas (CRISPR-associated) proteins mediates the different stages of this sophisticated immune response. Bioinformatic st...

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Bibliografische gegevens
Gepubliceerd in:RNA Biol
Hoofdauteurs: Hrle, Ajla, Maier, Lisa-Katharina, Sharma, Kundan, Ebert, Judith, Basquin, Claire, Urlaub, Henning, Marchfelder, Anita, Conti, Elena
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615900/
https://ncbi.nlm.nih.gov/pubmed/25483036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.29893
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