Noncoding regions of C. elegans mRNA undergo selective adenosine to inosine deamination and contain a small number of editing sites per transcript

ADARs (Adenosine deaminases that act on RNA) “edit” RNA by converting adenosines to inosines within double-stranded regions. The primary targets of ADARs are long duplexes present within noncoding regions of mRNAs, such as introns and 3′ untranslated regions (UTRs). Because adenosine and inosine hav...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Wheeler, Emily C, Washburn, Michael C, Major, Francois, Rusch, Douglas B, Hundley, Heather A
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615841/
https://ncbi.nlm.nih.gov/pubmed/25826568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1017220
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