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Positional changes of a pluripotency marker gene during structural reorganization of fibroblast nuclei in cloned early bovine embryos

Cloned bovine preimplantation embryos were generated by somatic cell nuclear transfer (SCNT) of bovine fetal fibroblasts with a silent copy of the pluripotency reporter gene GOF, integrated at a single site of a chromosome 13. GOF combines the regulatory Oct4/Pou5f1 sequence with the coding sequence...

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Vydáno v:Nucleus
Hlavní autoři: Popken, Jens, Koehler, Daniela, Brero, Alessandro, Wuensch, Annegret, Guengoer, Tuna, Thormeyer, Tobias, Wolf, Eckhard, Cremer, Thomas, Zakhartchenko, Valeri
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615807/
https://ncbi.nlm.nih.gov/pubmed/25495180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19491034.2014.970107
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