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Positional changes of a pluripotency marker gene during structural reorganization of fibroblast nuclei in cloned early bovine embryos

Cloned bovine preimplantation embryos were generated by somatic cell nuclear transfer (SCNT) of bovine fetal fibroblasts with a silent copy of the pluripotency reporter gene GOF, integrated at a single site of a chromosome 13. GOF combines the regulatory Oct4/Pou5f1 sequence with the coding sequence...

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Publicado en:Nucleus
Main Authors: Popken, Jens, Koehler, Daniela, Brero, Alessandro, Wuensch, Annegret, Guengoer, Tuna, Thormeyer, Tobias, Wolf, Eckhard, Cremer, Thomas, Zakhartchenko, Valeri
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615807/
https://ncbi.nlm.nih.gov/pubmed/25495180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19491034.2014.970107
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