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Conserved linker regions and their regulation determine multiple chromatin-binding modes of UHRF1

Ubiquitin-like with PHD and RING Finger domains 1 (UHRF1) is an important nuclear protein that is mutated and aberrantly expressed in many tumors. The protein integrates different chromatin modifications and is essential for their maintenance throughout the cell cycle. Separate chromatin-binding mod...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nucleus
Hauptverfasser: Tauber, Maria, Fischle, Wolfgang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615792/
https://ncbi.nlm.nih.gov/pubmed/25891992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2015.1026022
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