Blood Accessibility to Fibrin in Venous Thrombosis is Thrombus Age-Dependent and Predicts Fibrinolytic Efficacy: An In Vivo Fibrin Molecular Imaging Study

Fibrinolytic therapy of venous thromboembolism (VTE) is increasingly utilized, yet limited knowledge is available regarding in vivo mechanisms that govern fibrinolytic efficacy. In particular, it is unknown how age-dependent thrombus organization limits direct blood contact with fibrin, the target o...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Stein-Merlob, Ashley F., Kessinger, Chase W., Erdem, S. Sibel, Zelada, Henry, Hilderbrand, Scott A., Lin, Charles P., Tearney, Guillermo J., Jaff, Michael R., Reed, Guy L., Henke, Peter K., McCarthy, Jason R., Jaffer, Farouc A.
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615735/
https://ncbi.nlm.nih.gov/pubmed/26516370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.12494
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