Multifunctional nanoagent for thrombus-targeted fibrinolytic therapy

AIMS: Current thrombolytic therapies rely upon exogenous plasminogen activators (PA) to effectively lyse clots, thereby restoring blood flow and preventing tissue and organ death. Yet, these PAs may also impair normal hemostasis which may lead to life-threatening bleeding, including intracerebral he...

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Autors principals: McCarthy, Jason R., Sazonova, Irina Y., Erdem, S. Sibel, Hara, Tetsuya, Thompson, Brian D., Patel, Purvish, Botnaru, Ion, Lin, Charles P., Reed, Guy L., Weissleder, Ralph, Jaffer, Farouc A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360120/
https://ncbi.nlm.nih.gov/pubmed/22348271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.11.179
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