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Linker of nucleoskeleton and cytoskeleton (LINC) complex-mediated actin-dependent nuclear positioning orients centrosomes in migrating myoblasts

Myoblast migration is essential for muscle development and repair; however, the factors that contribute to the polarity of migrating myoblasts are relatively unknown. We find that randomly migrating C2C12 myoblasts orient their centrosomes in the direction of migration. Using wounded monolayers, we...

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書目詳細資料
發表在:Nucleus
Main Authors: Chang, Wakam, Antoku, Susumu, Östlund, Cecilia, Worman, Howard J, Gundersen, Gregg G
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615731/
https://ncbi.nlm.nih.gov/pubmed/25587885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2015.1004947
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