Linker of nucleoskeleton and cytoskeleton (LINC) complex-mediated actin-dependent nuclear positioning orients centrosomes in migrating myoblasts

Myoblast migration is essential for muscle development and repair; however, the factors that contribute to the polarity of migrating myoblasts are relatively unknown. We find that randomly migrating C2C12 myoblasts orient their centrosomes in the direction of migration. Using wounded monolayers, we...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleus
Egile Nagusiak: Chang, Wakam, Antoku, Susumu, Östlund, Cecilia, Worman, Howard J, Gundersen, Gregg G
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2015
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615731/
https://ncbi.nlm.nih.gov/pubmed/25587885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2015.1004947
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