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Linker of nucleoskeleton and cytoskeleton (LINC) complex-mediated actin-dependent nuclear positioning orients centrosomes in migrating myoblasts

Myoblast migration is essential for muscle development and repair; however, the factors that contribute to the polarity of migrating myoblasts are relatively unknown. We find that randomly migrating C2C12 myoblasts orient their centrosomes in the direction of migration. Using wounded monolayers, we...

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Podrobná bibliografie
Vydáno v:Nucleus
Hlavní autoři: Chang, Wakam, Antoku, Susumu, Östlund, Cecilia, Worman, Howard J, Gundersen, Gregg G
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615731/
https://ncbi.nlm.nih.gov/pubmed/25587885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2015.1004947
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