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Linker of nucleoskeleton and cytoskeleton (LINC) complex-mediated actin-dependent nuclear positioning orients centrosomes in migrating myoblasts

Myoblast migration is essential for muscle development and repair; however, the factors that contribute to the polarity of migrating myoblasts are relatively unknown. We find that randomly migrating C2C12 myoblasts orient their centrosomes in the direction of migration. Using wounded monolayers, we...

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Detalhes bibliográficos
Publicado no:Nucleus
Main Authors: Chang, Wakam, Antoku, Susumu, Östlund, Cecilia, Worman, Howard J, Gundersen, Gregg G
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615731/
https://ncbi.nlm.nih.gov/pubmed/25587885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2015.1004947
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