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Systems analysis of genetic variation in MPTP neurotoxicity in mice
We analyzed genetic variation in severity of neuronal damage using the known dopaminergic neurotoxicant, MPTP, as a prototypical chemical denervation agent. Male mice from ten members of the BXD family of recombinant inbred strains received 12.5 mg/kg MPTP s.c. (vs. saline) and 48 h later brains wer...
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Publicat a: | Neurotoxicology |
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Autors principals: | , , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
2013
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4615717/ https://ncbi.nlm.nih.gov/pubmed/23558233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2013.03.010 |
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