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Bile acid metabolism and signaling in cholestasis, inflammation and cancer

Bile acids are synthesized from cholesterol in the liver. Some cytochrome P450 (CYP) enzymes play key roles in bile acid synthesis. Bile acids are physiological detergent molecules, so are highly cytotoxic. They undergo enterohepatic circulation and play important roles in generating bile flow and f...

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Bibliografske podrobnosti
izdano v:Adv Pharmacol
Main Authors: Li, Tiangang, Apte, Udayan
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615692/
https://ncbi.nlm.nih.gov/pubmed/26233910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.apha.2015.04.003
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