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Bile acid metabolism and signaling in cholestasis, inflammation and cancer
Bile acids are synthesized from cholesterol in the liver. Some cytochrome P450 (CYP) enzymes play key roles in bile acid synthesis. Bile acids are physiological detergent molecules, so are highly cytotoxic. They undergo enterohepatic circulation and play important roles in generating bile flow and f...
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| Veröffentlicht in: | Adv Pharmacol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4615692/ https://ncbi.nlm.nih.gov/pubmed/26233910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.apha.2015.04.003 |
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