Compensatory Islet Response to Insulin Resistance Revealed by Quantitative Proteomics

Compensatory islet response is a distinct feature of the pre-diabetic insulin resistant state in humans and rodents. To identify alterations in the islet proteome that characterize the adaptive response, we analyzed islets from five-month-old male control, high-fat diet fed (HFD) or obese ob/ob mice...

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Pubblicato in:J Proteome Res
Autori principali: El Ouaamari, Abdelfattah, Zhou, Jian-Ying, Liew, Chong Wee, Shirakawa, Jun, Dirice, Ercument, Gedeon, Nicholas, Kahraman, Sevim, De Jesus, Dario F., Bhatt, Shweta, Kim, Jong-Seo, Clauss, Therese RW, Camp, David G., Smith, Richard D., Qian, Wei-Jun, Kulkarni, Rohit N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615688/
https://ncbi.nlm.nih.gov/pubmed/26151086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.5b00587
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