Maxizyme-mediated specific inhibition on mutant-type p53 in vitro

AIM: To evaluate the specific inhibition of maxizyme directing against mutant-type p53 gene (mtp53) at codon 249 in exon 7 (AGG→AGT) in vitro. METHODS: Two different monomers of anti-mtp53 maxizyme (maxizyme right MzR, maxizyme left MzL) and control mutant maxizyme (G(5)→A(5)) were designed by compu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:World J Gastroenterol
Prif Awduron: Kong, Xin-Juan, Song, Yu-Hu, Lin, Ju-Sheng, Huang, Huan-Jun, Wang, Nan-Xia, Liu, Nan-Zhi, Li, Bin, Jin, You-Xin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Baishideng Publishing Group Inc 2003
Pynciau:
Basic Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615507/
https://ncbi.nlm.nih.gov/pubmed/12854166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v9.i7.1571
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