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Maxizyme-mediated specific inhibition on mutant-type p53 in vitro
AIM: To evaluate the specific inhibition of maxizyme directing against mutant-type p53 gene (mtp53) at codon 249 in exon 7 (AGG→AGT) in vitro. METHODS: Two different monomers of anti-mtp53 maxizyme (maxizyme right MzR, maxizyme left MzL) and control mutant maxizyme (G(5)→A(5)) were designed by compu...
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| Publicado no: | World J Gastroenterol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Baishideng Publishing Group Inc
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4615507/ https://ncbi.nlm.nih.gov/pubmed/12854166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v9.i7.1571 |
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