Mutations outside the YMDD motif in the P protein can also cause DHBV resistant to Lamivudine

AIM: To observe the Lamivudine resistance character of a DHBV strain in vitro and in vivo, and to analyze if the Lamivudine resistance character is caused by gene mutation or by abnormity of the Lamivudine metabolism. METHODS: Congenitally DHBV-negative Guangdong brown ducks and duck embryo liver ce...

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Bibliographic Details
Published in:World J Gastroenterol
Main Authors: He, Jin-Yang, Zhu, Yu-Tong, Yang, Rui-Yi, Feng, Li-Ling, Guo, Xing-Bo, Zhang, Feng-Xue, Chen, Hong-Shan
Format: Artigo
Language:Inglês
Published: Baishideng Publishing Group Inc 2005
Subjects:
Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615456/
https://ncbi.nlm.nih.gov/pubmed/16015703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i27.4261
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