Prevalence, Incidence, and Clinical Relevance of the Reverse Transcriptase V207I Mutation Outside the YMDD Motif of the Hepatitis B Virus Polymerase during Lamivudine Therapy

The reverse transcriptase V207I mutation within the hepatitis B virus (HBV) polymerase is associated with resistance to lamivudine in vitro. The prevalence of this mutation in treatment-naïve patients was 1% (1/96). A follow-up of the patient carrying this mutation prior to treatment revealed no los...

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Detalhes bibliográficos
Main Authors: Zöllner, B., Sterneck, M., Wursthorn, K., Petersen, J., Schröter, M., Laufs, R., Feucht, H.-H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Virology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1153772/
https://ncbi.nlm.nih.gov/pubmed/15872296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.43.5.2503-2505.2005
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