The Aplidin analogs PM01215 and PM02781 inhibit angiogenesis in vitro and in vivo

BACKGROUND: Novel synthesized analogs of Aplidin, PM01215 and PM02781, were tested for antiangiogenic effects on primary human endothelial cells in vitro and for inhibition of angiogenesis and tumor growth in vivo. METHODS: Antiangiogenic activity of both derivatives was evaluated by real-time cell...

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Vydáno v:BMC Cancer
Hlavní autoři: Borjan, Bojana, Steiner, Normann, Karbon, Silvia, Kern, Johann, Francesch, Andrés, Hermann, Martin, Willenbacher, Wolfgang, Gunsilius, Eberhard, Untergasser, Gerold
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615365/
https://ncbi.nlm.nih.gov/pubmed/26483043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1729-4
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