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High Expression of Pyruvate Kinase M2 is Associated with Chemosensitivity to Epirubicin and 5-Fluorouracil in Breast Cancer

Background: Pyruvate kinase M2 (PKM2) is the key enzyme in the Warburg effect, and it was recently reported to be involved in the metabolic pathways of chemotherapeutic drugs. However, the role of PKM2 in breast cancer and its influence in the sensitivity to front-line anticancer drugs remains uncle...

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Dettagli Bibliografici
Pubblicato in:J Cancer
Autori principali: Lin, Yang, Lv, Feng, Liu, Fangfang, Guo, Xiaojing, Fan, Yu, Gu, Feng, Gu, Jun, Fu, Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615349/
https://ncbi.nlm.nih.gov/pubmed/26516361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.12719
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