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Apatinib enhances chemosensitivity of gastric cancer to paclitaxel and 5-fluorouracil

Background and aim: Paclitaxel (PTX) plus 5-fluorouracil (5-Fu) has become the standard chemotherapy for advanced gastric cancer (GC). Apatinib, a small-molecule tyrosine kinase inhibitor targeting vascular endothelial growth factor receptor-2, improves outcomes in GC patients as a third-line treatm...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Xu, Zhiyuan, Hu, Can, Chen, Shangqi, Zhang, Chunli, Yu, Jianfa, Wang, Xiaofeng, Lv, Hang, Cheng, Xiangdong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549793/
https://ncbi.nlm.nih.gov/pubmed/31213909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S196372
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