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Involvement of gelsolin in TGF-beta 1 induced epithelial to mesenchymal transition in breast cancer cells

BACKGROUND: Increasing evidence suggests that transforming growth factor-beta 1 (TGF-β1) triggers epithelial to mesenchymal transition (EMT) and facilitates breast cancer stem cell differentiation. Gelsolin (GSN) is a ubiquitous actin filament-severing protein. However, the relationship between the...

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Bibliographische Detailangaben
Veröffentlicht in:J Biomed Sci
Hauptverfasser: Chen, Zhi-Yuan, Wang, Pei-Wen, Shieh, Dar-Bin, Chiu, Kuan-Ying, Liou, Ying-Ming
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615330/
https://ncbi.nlm.nih.gov/pubmed/26482896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-015-0197-0
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