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Implications of polyadenylation in health and disease

Polyadenylation is the RNA processing step that completes the maturation of nearly all eukaryotic mRNAs. It is a two-step nuclear process that involves an endonucleolytic cleavage of the pre-mRNA at the 3′-end and the polymerization of a polyadenosine (polyA) tail, which is fundamental for mRNA stab...

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Detalhes bibliográficos
Publicado no:Nucleus
Main Authors: Curinha, Ana, Oliveira Braz, Sandra, Pereira-Castro, Isabel, Cruz, Andrea, Moreira, Alexandra
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615197/
https://ncbi.nlm.nih.gov/pubmed/25484187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.36360
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