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Alterations in Polyadenylation and Its Implications for Endocrine Disease

Introduction: Polyadenylation is the process in which the pre-mRNA is cleaved at the poly(A) site and a poly(A) tail is added – a process necessary for normal mRNA formation. Genes with multiple poly(A) sites can undergo alternative polyadenylation (APA), producing distinct mRNA isoforms with differ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rehfeld, Anders, Plass, Mireya, Krogh, Anders, Friis-Hansen, Lennart
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647115/
https://ncbi.nlm.nih.gov/pubmed/23658553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2013.00053
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