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FMRP interacts with G-quadruplex structures in the 3’-UTR of its dendritic target Shank1 mRNA
Fragile X syndrome (FXS), the most common cause of inherited intellectual disability, is caused by the loss of expression of the fragile X mental retardation protein (FMRP). FMRP, which regulates the transport and translation of specific mRNAs, uses its RGG box domain to bind mRNA targets that form...
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| Vydáno v: | RNA Biol |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4615183/ https://ncbi.nlm.nih.gov/pubmed/25692235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2014.996464 |
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