FMRP interacts with G-quadruplex structures in the 3’-UTR of its dendritic target Shank1 mRNA

Fragile X syndrome (FXS), the most common cause of inherited intellectual disability, is caused by the loss of expression of the fragile X mental retardation protein (FMRP). FMRP, which regulates the transport and translation of specific mRNAs, uses its RGG box domain to bind mRNA targets that form...

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Bibliografische gegevens
Gepubliceerd in:RNA Biol
Hoofdauteurs: Zhang, Yang, Gaetano, Christian M, Williams, Kathryn R, Bassell, Gary J, Mihailescu, Mihaela Rita
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2015
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Research Papers
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615183/
https://ncbi.nlm.nih.gov/pubmed/25692235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2014.996464
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