Novel GHRH antagonists suppress the growth of human malignant melanoma by restoring nuclear p27 function

Malignant melanoma is the deadliest form of skin cancer; the treatment of advanced and recurrent forms remains a challenge. It has recently been reported that growth hormone-releasing hormone (GHRH) receptor is involved in the pathogenesis of melanoma. Therefore, we investigated the effects of our n...

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Veröffentlicht in:Cell Cycle
Hauptverfasser: Szalontay, Luca, Schally, Andrew V, Popovics, Petra, Vidaurre, Irving, Krishan, Awtar, Zarandi, Marta, Cai, Ren-Zhi, Klukovits, Anna, Block, Norman L, Rick, Ferenc G
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615138/
https://ncbi.nlm.nih.gov/pubmed/25486366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2015.945879
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