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Cell divisions are not essential for the direct conversion of fibroblasts into neuronal cells

Direct lineage conversion is a promising approach for disease modeling and regenerative medicine. Cell divisions play a key role in reprogramming of somatic cells to pluripotency, however their role in direct lineage conversion is not clear. Here we used transdifferentiation of fibroblasts into neur...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Fishman, VS, Shnayder, TA, Orishchenko, KE, Bader, M, Alenina, N, Serov, OL
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615072/
https://ncbi.nlm.nih.gov/pubmed/25695848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1012875
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