KSHV latent protein LANA2 inhibits sumo2 modification of p53

Tumor suppressor p53 plays a crucial antiviral role and targeting of p53 by viral proteins is a common mechanism involved in virus oncogenesis. The activity of p53 is tightly regulated at the post-translational levels through a myriad of modifications. Among them, modification of p53 by SUMO has bee...

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Veröffentlicht in:Cell Cycle
Hauptverfasser: Laura, Marcos-Villar, de la Cruz-Herrera, Carlos F, Ferreirós, Alba, Baz-Martínez, Maite, Lang, Valerie, Vidal, Anxo, Muñoz-Fontela, Cesar, Rodríguez, Manuel S, Collado, Manuel, Rivas, Carmen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615004/
https://ncbi.nlm.nih.gov/pubmed/25607652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.980657
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