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p27(Kip1) participates in the regulation of endoreplication in differentiating chick retinal ganglion cells

Nuclear DNA duplication in the absence of cell division (i.e. endoreplication) leads to somatic polyploidy in eukaryotic cells. In contrast to some invertebrate neurons, whose nuclei may contain up to 200,000-fold the normal haploid DNA amount (C), polyploid neurons in higher vertebrates show only 4...

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Publicado en:Cell Cycle
Main Authors: Ovejero-Benito, María C, Frade, José M
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614947/
https://ncbi.nlm.nih.gov/pubmed/25946375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1044175
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