Centralspindlin assembly and 2 phosphorylations on MgcRacGAP by Polo-like kinase 1 initiate Ect2 binding in early cytokinesis

Cytokinesis is the final step of cell division which partitions genetic and cytosolic content into daughter cells. Failed cytokinesis causes polyploidy, genetic instability, and cancer. Kinases use phosphorylation to regulate the timing and location of the cytokinetic furrow. Polo-like kinase 1 (Plk...

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Publicado en:Cell Cycle
Autores principales: Kim, Hyunjung, Guo, Feng, Brahma, Sarang, Xing, Yongna, Burkard, Mark E
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614826/
https://ncbi.nlm.nih.gov/pubmed/25486482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.947201
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