The mitochondria-targeted antioxidant SkQ1 restores αB-crystallin expression and protects against AMD-like retinopathy in OXYS rats

Age-related macular degeneration (AMD), a neurodegenerative and vascular retinal disease, is the leading cause of blindness in the developed world. Accumulating evidence suggests that alterations in the expression of a small heat shock protein (αB-crystallin) are involved in the pathogeneses of AMD....

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Bibliografiske detaljer
Udgivet i:Cell Cycle
Main Authors: Muraleva, Natalia A, Kozhevnikova, Oyuna S, Zhdankina, Anna A, Stefanova, Natalia A, Karamysheva, Tatyana V, Fursova, Anzhella Z, Kolosova, Nataliya G
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2014
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614531/
https://ncbi.nlm.nih.gov/pubmed/25483086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.958393
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