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Suppression of AMD-Like Pathology by Mitochondria-Targeted Antioxidant SkQ1 Is Associated with a Decrease in the Accumulation of Amyloid β and in mTOR Activity

Age-related macular degeneration (AMD) is a major cause of irreversible visual impairment and blindness in developed countries, and the molecular pathogenesis of AMD is poorly understood. Recent studies strongly indicate that amyloid β (Aβ) accumulation —found in the brain and a defining feature of...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antioxidants (Basel)
Prif Awduron: Muraleva, Natalia A., Kozhevnikova, Oyuna S., Fursova, Anzhela Z., Kolosova, Nataliya G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6616484/
https://ncbi.nlm.nih.gov/pubmed/31208023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox8060177
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