Inhibition of CDK-mediated phosphorylation of Smad3 results in decreased oncogenesis in triple negative breast cancer cells

Breast cancer onset and disease progression have been linked to members of the TGFβ superfamily and their downstream signaling components, the Smads. Alterations in Smad3 signaling are associated with the dichotomous role of TGFβ in malignancy, mediating both tumor suppressant and pro-metastatic beh...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Cycle
Prif Awduron: Tarasewicz, Elizabeth, Rivas, Lisbi, Hamdan, Randala, Dokic, Danijela, Parimi, Vamsi, Bernabe, Beatriz Penalver, Thomas, Alexandra, Shea, Lonnie D, Jeruss, Jacqueline S
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2014
Pynciau:
Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614520/
https://ncbi.nlm.nih.gov/pubmed/25485498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.950126
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