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PML represses lung cancer metastasis by suppressing the nuclear EGFR-mediated transcriptional activation of MMP2
Promyelocytic leukemia protein (PML) is emerging as an important tumor suppressor. Its expression is lost during the progression of several types of cancer, including lung cancer. The EGF receptor (EGFR), a membrane-bound receptor tyrosine kinase, transduces intracellular signals responsible for cel...
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Publicado no: | Cell Cycle |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4614437/ https://ncbi.nlm.nih.gov/pubmed/25486572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.949212 |
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