DNA-PKcs plays role in cancer metastasis through regulation of secreted proteins involved in migration and invasion

The DNA-dependent protein kinase catalytic subunit (DNA-PKcs) plays a major role in DNA damage signaling and repair and is also frequently overexpressed in tumor metastasis. We used isogenic cell lines expressing different levels of DNA-PKcs to investigate the role of DNA-PKcs in metastatic developm...

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發表在:Cell Cycle
Main Authors: Kotula, Ewa, Berthault, Nathalie, Agrario, Celine, Lienafa, Marie-Christine, Simon, Anthony, Dingli, Florent, Loew, Damarys, Sibut, Vonick, Saule, Simon, Dutreix, Marie
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614356/
https://ncbi.nlm.nih.gov/pubmed/26017556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1026522
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